Major Depressive Disorder
Major Depressive Disorder, also known as clinical depression or simply depression, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in previously enjoyed activities.

What is a Major Depressive Disorder?
Major Depressive Disorder, also known as clinical depression or simply depression, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in previously enjoyed activities. Other symptoms may include changes in appetite and sleep patterns, fatigue, difficulty concentrating, and thoughts of death or suicide. Depression is a serious illness that can significantly impact a person's daily functioning and quality of life. It is estimated to affect millions of people worldwide and can occur at any age. Depression is typically diagnosed by a mental health professional after a comprehensive evaluation and is treated with a combination of medications, therapy, and lifestyle changes.
How does Major Depressive Disorder affect someone?
Major Depressive Disorder can affect people of any age, race, ethnicity, or gender. According to the World Health Organization (WHO), depression is a leading cause of disability worldwide, affecting an estimated 264 million people.
Depression can affect people of all walks of life, regardless of their financial, social, or personal circumstances. It is a common and complex condition that can occur because of a combination of genetic, environmental, and psychological factors.
Women are more likely to experience depression than men, and the risk of depression can increase with age. Other factors that can increase the risk of depression include a family history of depression, a history of trauma or abuse, chronic medical conditions, and certain medications. However, it is important to note that depression can occur in anyone, and it is not a sign of weakness or a personal failing.
What are symptoms of a Major Depressive Disorder?
The symptoms of major depressive disorder can vary from person to person, but common signs and symptoms include:
Persistent feelings of sadness, hopelessness, and emptiness
Loss of interest or pleasure in previously enjoyed activities
Changes in appetite, leading to significant weight loss or gain
Changes in sleep patterns, such as insomnia or excessive sleeping
Fatigue or loss of energy
Difficulty concentrating, remembering, or making decisions
Feelings of worthlessness or guilt
Thoughts of death or suicide
Physical symptoms such as headaches, stomachaches, or chronic pain that do not respond to treatment.
Note that these symptoms must persist for at least two weeks and significantly interfere with a person's daily functioning to be diagnosed with Major Depressive Disorder. If you or someone you know is experiencing symptoms of depression, it is important to seek help from a mental health professional.
What are the diagnosis criteria for a Major Depressive Disorder?
The diagnosis of major depressive disorder is made based on the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is published by the American Psychiatric Association. The DSM-5 criteria for major depressive disorder include:
A persistent and pervasive feeling of sadness, hopelessness, and/or emptiness for at least two weeks.
A significant loss of interest or pleasure in previously enjoyed activities.
Changes in appetite or sleep patterns.
Fatigue or loss of energy.
Feelings of worthlessness or excessive guilt.
Difficulty concentrating, making decisions, or remembering.
Thoughts of death or suicide, or a suicide attempt.
To be diagnosed with major depressive disorder, an individual must have at least five of these symptoms, and at least one of the symptoms must be either a persistent feeling of sadness or a significant loss of interest or pleasure in activities. The symptoms must also cause clinically significant distress or impairment in social, occupational, or other key areas of functioning.
It is important to note that the symptoms must not be due to a medical condition, substance use, or medication side effects. A mental health professional, such as a psychologist or psychiatrist, will perform a comprehensive evaluation, including a medical and psychiatric history, to make an accurate diagnosis.
What are strategies and treatments for overcoming Major Depressive Disorder?
The treatment of major depressive disorder typically involves a combination of medication, psychotherapy, and lifestyle changes. The specific treatment plan will depend on the individual's symptoms, medical history, and personal preferences.
Medications: Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants, can be effective in reducing the symptoms of depression.
Psychotherapy: Talking with a mental health professional, such as a psychologist or psychiatrist, can help individuals with depression understand and manage their emotions, thoughts, and behaviors. Cognitive behavioral therapy (CBT) and interpersonal therapy (IPT) are two commonly used forms of psychotherapy for depression.
Lifestyle changes: Making changes to one's lifestyle, such as regular exercise, a balanced diet, and stress-management techniques, can also help reduce the symptoms of depression.
Electroconvulsive therapy (ECT): ECT is a medical procedure that uses electrical stimulation to treat severe depression that does not respond to other treatments.
Light therapy: Light therapy, also known as phototherapy, involves exposure to bright light, usually from a special light box, to help regulate the body's natural sleep-wake cycle.
It is important to work closely with a mental health professional to determine the best course of treatment for major depressive disorder. In some cases, a combination of treatments may be recommended. The goal of treatment is to relieve symptoms, improve daily functioning, and prevent future episodes of depression.
This content is provided for informational and entertainment value only. It is not a replacement for a trained professional's diagnosis or for the treatment of any illness. If you feel like you are struggling with this condition, it is important to seek help from a mental health professional. With the right treatment and support, individuals with this condition can learn to manage their symptoms and lead fulfilling lives. BetterPsych provides full psychological services via telehealth and offers a 100% satisfaction guarantee on our services. For more information and to find a therapist specializing in this disorder, please call (833) 496-5011, or visit https://www.betterpsych.com.